With the announcement that Patricia Wettig will be leaving the series, many fans are left wondering how Fox can fill the void left on Prison Break. Patricia Wettig will be joining Brothers & Sisters, and John Billingsley (who plays Wettig’s brother—the victim of the set-up that framed Lincoln Burrows) is leaving for The Nine. Billingsly’s face was never really revealed on the show, so it was easy enough to replace the actor with Jeff Perry, who has appeared on Grey’s Anatomy and Nash Bridges. According to series creator Paul Scheuring, Wettig is “not out of the picture yet.” The plan is for her storyline—and that of the conspiracy to set up Burrows—to take a backseat during the initial episodes, as the focus now will be on the manhunt for Lincoln, Michael Scofield (Wentworth Miller) and the other escapees. Scheuring says, “In the early part of the season, it’s really going to be much more about the immediacy of having to get the hell away from the pursuit.”

Luckily, we don’t have to wait too long for the new season to start. Prison Break begins on Monday, August 21st.