Following her rise to fame on ER, Julianna Margulies left the show for what promised to be bigger things. Then she seemed to leave the spotlight, with movie roles here and there, but nothing too memorable. Now Margulies returns to the small screen for a Sci Fi Channel limited series, titled The Lost Room. In it, she plays a woman who contacts a detective (played by Peter Krause) about the death of her brother – who was killed for a motel room key that unlocks a room full of power. The six-hour series will premiere in December. Margulies will also appear in upcoming episodes of The Sopranos and in the film Snakes on a Plane, with Samuel L. Jackson.