Unlike most Mike Tyson fights, The Hangover‘s win was no knockout.

After a back-and-forth battle with Up, Todd Phillips’ film about an eventful bachelor party edged out the animated pic by less than $1 million. Hangover - which features no major stars (unless you count the boxer) - grossed nearly $45 million on its opening weekend. That’s the third best debut for an R-rated comedy ever. (Only Sex and the City and American Pie 2 have done better.)

Meanwhile, a project actually featuring an A-lister became the summer’s first stinker. Land of the Lost, starring Will Ferrell, Anna Friel and Danny McBride, earned a sad $18.8 million over the past three days. Although that amount was good enough for third place, the film cost an estimated $100 million to make.

1. The Hangover, Warner Bros., $44,979,319 (avg. $13,759)
2. Up, Disney/Pixar, $44,138,266 (avg. $11,561)
3. Land of the Lost, Universal, $18,837,350 (avg. $5350)
4. Night at the Museum: Battle of the Smithsonian, 20th Century Fox, $14,634,988 (avg. $3844)
5. Star Trek, Paramount, $8,310,480 (avg. $2595)
6. Terminator Salvation, Warner Bros., $8,248,387 (avg. $2496)
7. Drag Me to Hell, Universal, $7,040,550 (avg. $2805)
8. Angels & Demons, Sony, $6,550,282 (avg. $2239)
9. My Life in Ruins, Fox Searchlight, $3,223,161 (avg. $2769)
10. Dance Flick, Paramount, $1,958,725 (avg. $1147)

(You can review last week’s numbers here.)